Pyari Behna is an action-comedy drama. The movie revolves around a young man named Kali (Mithun Chakraborty), who lives with his sister Seeta (Tanvi Azmi) in a shanty house, and works at a railway station with an Engineer named Vinay (Vinod Mehra). Kali and Seeta’s friend, Mangala (Padmini Kohlapure) fall in love with each other and get married. However, soon after their wedding, Kali meets with an accident and loses his arm, and holds Vinay responsible for his condition. Later, when Vinay meets Kali’s sister, he falls in love with her. However, Kali is against the match, as he holds Vinay responsible for the accident. Will Vinay ever be able to convince Kali for the match?