Ustadi Ustad Se is an action crime drama. The movie follows the story of a young girl named Seema (Ranjeeta Kaur), who lives with her maternal grandmother and uncle in a small town. Seema is best friends with Rajesh (Mithun Chakraborty), and things go well for the two. However, their lives take a turn, when floods create destruction in the region, and Seema is separated from Rajesh. Years later, Seema is rejoiced when she unites again with Rajesh, and her grandmother arranges their marriage. However, on the day of the wedding, a woman with a child stops the marriage and claims that Rajesh is the father of her child. How this newly learnt information impacts Seema’s life forms the rest of the plot of the movie.